Informal experiments have proven that overdose will cause physical pain including heart palpitations, vertigo and sedation at Significantly decrease than dangerous doses, ordinarily causing the user to endure significant quantities of nervousness or to slide asleep.
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dimethylamino group greatly boosts the MOR affinity, as in U-47700. Against this, embedding that very same standard nitrogen into a cyclic pyrrolidine ring tremendously enhances the KOR affinity, as in U-50488. MOR/KOR selectivity is influenced with the N
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